Modified Growth Releasing Factor aminos 1-29, usually referred to as Modified GRF (1-29) or Mod GRF(1-29), also known as CJC-1295 without DAC, is a synthetic analog of the endogenous peptide signalling hormone Growth Hormone Releasing Hormone (GHRH).
CJC-1295 no DAC is a Long acting GHRH analog. Growth-hormone-releasing hormone (GHRH), also known as growth-hormone-releasing factor (GRF or GHRF) or somatocrinin, is a 44-amino acid peptide hormone produced in the hypothalamus by the arcuate nucleus. GHRH stimulates growth hormone (GH) secretion from the pituitary. GHRH is released in a pulsatile manner, stimulating pulsatile release of GH respectively.
This substance also promotes slow wave sleep. The active portion of this GRF or GHRH peptide can be found as a 29 amino acid long peptide and is appropriately named GHRH 1-29. This pulsatile release of various peptides is due to the negative feedback loop that is part of the hGH axis and controls the amount of hGH that your body produces to keep it in a homeostatic environment.
CJC NO DAC
CJC-1295 no DAC in vivo and the Journal of Clinical Endocrinology & Metabolism has reported dose-dependent increases in mean plasma GH concentrations by 2-10 fold for more than 6 days and increased IGF-1 concentrations 1.5-3 fold for 9-11 days after a single injection.